Structure of PDB 4nqx Chain E

Receptor sequence
>4nqxE (length=275) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQKMEPRAP
WIEQEGPEYWDQETRNMKAHSQTDRANLGTLRGYYNQSEDGSHTIQIMYG
CDVGPDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAV
HAAEQRRVYLEGRCVDGLRRYLENGKETLQRTDPPKTHMTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWE
3D structure
PDB4nqx Preexisting CD8+ T-cell immunity to the H7N9 influenza A virus varies across ethnicities.
ChainE
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide E Y7 E63 N66 M67 H70 T73 N77 L81 Y84 I95 Y99 D116 T143 K146 W147 R156 Y159 R163 Y171 Y7 E63 N66 M67 H70 T73 N77 L81 Y84 I95 Y99 D116 T143 K146 W147 R156 Y159 R163 Y171
BS02 peptide E T225 Q226 D227 T225 Q226 D227
External links
PDB RCSB:4nqx, PDBe:4nqx, PDBj:4nqx
PDBsum4nqx
PubMed24395804
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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