Structure of PDB 4m63 Chain E

Receptor sequence
>4m63E (length=350) Species: 7227 (Drosophila melanogaster) [Search protein sequence]
AALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPGDEAQSKRGILYPIEHG
IVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMF
ETFNTPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHA
ILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFE
QEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMEACGI
HETTYNSIMKCAAAIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPST
MKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKC
3D structure
PDB4m63 The Bacterial Effector VopL Organizes Actin into Filament-like Structures.
ChainE
Resolution2.748 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP E G13 S14 G15 K18 G156 D157 G182 K213 E214 G302 M305 Y306 K336 G8 S9 G10 K13 G132 D133 G158 K189 E190 G278 M281 Y282 K312
BS02 CA E D11 Q137 D6 Q113
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016787 hydrolase activity
Biological Process
GO:0000281 mitotic cytokinesis
GO:0006338 chromatin remodeling
GO:0007291 sperm individualization
GO:0030723 ovarian fusome organization
GO:0032507 maintenance of protein location in cell
GO:0035148 tube formation
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0031011 Ino80 complex
GO:0035060 brahma complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4m63, PDBe:4m63, PDBj:4m63
PDBsum4m63
PubMed24120140
UniProtP10987|ACT1_DROME Actin-5C (Gene Name=Act5C)

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