Structure of PDB 4l18 Chain E

Receptor sequence
>4l18E (length=141) Species: 10090 (Mus musculus) [Search protein sequence]
VEVLADHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALGDVPDGT
LVTVMAGNDENYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTIT
VFTNPPQVATYHRAIKITVDGPREPRGSLSFSERLSELEQL
3D structure
PDB4l18 Structural basis of Ets1 activation by Runx1.
ChainE
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna E R139 R142 G143 K167 V170 D171 R88 R91 G92 K116 V119 D120
BS02 dna E R80 K83 R135 R142 R174 R177 R29 K32 R84 R91 R123 R126
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005524 ATP binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4l18, PDBe:4l18, PDBj:4l18
PDBsum4l18
PubMed24646888
UniProtQ03347|RUNX1_MOUSE Runt-related transcription factor 1 (Gene Name=Runx1)

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