Structure of PDB 4l17 Chain E

Receptor sequence
>4l17E (length=259) Species: 10116 (Rattus norvegicus) [Search protein sequence]
NKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYK
LTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITYVREEVIDF
SKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKI
CVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQ
RKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKN
KWWYDKGEC
3D structure
PDB4l17 A conformational intermediate in glutamate receptor activation.
ChainE
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 DNQ E Y16 Y61 P89 L90 T91 R96 T174 E193 M196 Y220 Y14 Y59 P87 L88 T89 R94 T172 E191 M194 Y218
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:4l17, PDBe:4l17, PDBj:4l17
PDBsum4l17
PubMed23931998
UniProtP19491|GRIA2_RAT Glutamate receptor 2 (Gene Name=Gria2)

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