Structure of PDB 4j9i Chain E

Receptor sequence
>4j9iE (length=57) Species: 9606 (Homo sapiens) [Search protein sequence]
NLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQGWVPS
NYITPVN
3D structure
PDB4j9i Crystallization by capillary counter-diffusion and structure determination of the N114A mutant of the SH3 domain of Abl tyrosine kinase complexed with a high-affinity peptide ligand.
ChainE
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide E Y70 D77 W99 W110 P112 N114 Y115 Y7 D14 W36 W47 P49 N51 Y52
External links
PDB RCSB:4j9i, PDBe:4j9i, PDBj:4j9i
PDBsum4j9i
PubMed
UniProtP00519|ABL1_HUMAN Tyrosine-protein kinase ABL1 (Gene Name=ABL1)

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