Structure of PDB 4j4v Chain E

Receptor sequence
>4j4vE (length=240) Species: 1205901 (Phlebovirus JS2010-018) [Search protein sequence]
SEWSRIAVEFGEQQLNLTELEDFARELAYEGLDPALIIKKLKETGGDDWV
KDTKFIIVFALTRGNKIVKASGKMSNSGSKRLMALQEKYGLVERAETRLS
ITPVRVAQSLPTWTCAAAAALKEYLPVGPAVMNLKVENYPPEMMCMAFGS
LIPTAGVSEATTKTLMEAYSLWQDAFTKTINGASKTEVYNSFRDPLHAAV
NSVFFPNDVRVKWLKAKGILGPDGVPSRAAEVAAAAYRNL
3D structure
PDB4j4v Structure of severe Fever with thrombocytopenia syndrome virus nucleocapsid protein in complex with suramin reveals therapeutic potential
ChainE
Resolution2.303 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SVR E T63 R64 G65 N66 R95 A96 M147 F177 T62 R63 G64 N65 R94 A95 M146 F176 PDBbind-CN: -logKd/Ki=6.36,Kd=0.44uM
Gene Ontology
Cellular Component
GO:0019013 viral nucleocapsid
GO:0019028 viral capsid
GO:0030430 host cell cytoplasm
GO:0042025 host cell nucleus
GO:0044172 host cell endoplasmic reticulum-Golgi intermediate compartment
GO:0044177 host cell Golgi apparatus
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:4j4v, PDBe:4j4v, PDBj:4j4v
PDBsum4j4v
PubMed23576501
UniProtI6WJ72|NCAP_SFTS Nucleoprotein (Gene Name=NP)

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