Structure of PDB 4f21 Chain E

Receptor sequence
>4f21E (length=206) Species: 177416 (Francisella tularensis subsp. tularensis SCHU S4) [Search protein sequence]
SNAMNYELMEPAKQARFCVIWLHGLGHDFVDIVNYFDVSLDEIRFIFPHA
DIGMQMRAWYDIKSVDVEGINSSIAKVNKLIDSQVNQGIASENIILAGFS
QGGIIATYTAITSQRKLGGIMALSTYLPAWDNFKGKITSINKGLPILVCH
GTDDQVLPEVLGHDLSDKLKVSGFANEYKHYVGMQHSVCMEEIKDISNFI
AKTFKI
3D structure
PDB4f21 Large scale structural rearrangement of a serine hydrolase from Francisella tularensis facilitates catalysis.
ChainE
Resolution2.5 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) L22 S116 N157 D170 H202
Catalytic site (residue number reindexed from 1) L25 S100 N141 D154 H186
Enzyme Commision number 3.1.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 0S1 E S116 Q117 H202 S100 Q101 H186
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity

View graph for
Molecular Function
External links
PDB RCSB:4f21, PDBe:4f21, PDBj:4f21
PDBsum4f21
PubMed23430251
UniProtQ5NI32

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