Structure of PDB 4f1e Chain E

Receptor sequence
>4f1eE (length=65) Species: 9606 (Homo sapiens) [Search protein sequence]
KAMINLHIQKDNPKIVHAFDMEDLGGKAVYCRCWRSKKFPFCDGAHTKHN
EETGDNVGPLIIKKK
3D structure
PDB4f1e Allosteric control in a metalloprotein dramatically alters function.
ChainE
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.6.1.3: cysteine transaminase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FES E C72 R73 C74 C83 D84 G85 A86 H87 C31 R32 C33 C42 D43 G44 A45 H46
Gene Ontology
Molecular Function
GO:0051537 2 iron, 2 sulfur cluster binding
Biological Process
GO:0010506 regulation of autophagy
Cellular Component
GO:0043231 intracellular membrane-bounded organelle

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Molecular Function
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Cellular Component
External links
PDB RCSB:4f1e, PDBe:4f1e, PDBj:4f1e
PDBsum4f1e
PubMed23271805
UniProtQ9NZ45|CISD1_HUMAN CDGSH iron-sulfur domain-containing protein 1 (Gene Name=CISD1)

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