Structure of PDB 4e2s Chain E

Receptor sequence
>4e2sE (length=258) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
PIYWKATNPTLSPSHLQDLPGFTRSVYKRDHALITPESHVYSPLPDWTNT
LGAYLITPATGSHFVMYLAKMKEMSSSGLPPQDIERLIFVVEGAVTLTNS
SSKKLTVDSYAYLPPNFHHSLDCVESATLVVFERRYEYLGSHTTELIVGS
TDKQPLLETPGEVFELRKLLPMSVAYDFNIHTMDFQPGEFLNVKEVHYNQ
HGLLLLEGQGIYRLGDNWYPVQAGDVIWMAPFVPQWYAALGKTRSRYLLY
KDVNRNPL
3D structure
PDB4e2s Structural and functional insights into (S)-ureidoglycine aminohydrolase, key enzyme of purine catabolism in Arabidopsis thaliana
ChainE
Resolution2.59 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.5.3.26: (S)-ureidoglycine aminohydrolase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN E E235 H237 H241 Q275 E195 H197 H201 Q235
BS02 UGY E M223 E235 H241 Y252 Q275 Y287 L289 M183 E195 H201 Y212 Q235 Y247 L249
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
GO:0071522 ureidoglycine aminohydrolase activity
Biological Process
GO:0000256 allantoin catabolic process
GO:0006144 purine nucleobase metabolic process
GO:0006145 purine nucleobase catabolic process
GO:0006355 regulation of DNA-templated transcription
GO:0010136 ureide catabolic process
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4e2s, PDBe:4e2s, PDBj:4e2s
PDBsum4e2s
PubMed22493446
UniProtQ8GXV5|UGHY_ARATH (S)-ureidoglycine aminohydrolase (Gene Name=UGLYAH)

[Back to BioLiP]