Structure of PDB 4cyi Chain E

Receptor sequence
>4cyiE (length=394) Species: 209285 (Thermochaetoides thermophila) [Search protein sequence]
TYDFFMPQNLREDLQKKQFATLQVIPNSGLPQLEHWHSLVPLDTSNRKNT
SCFGYPSWVYKAQNSRNGRHYALRRLEGYRLTNEKAILNVMKDWKKIKNA
SIVTIHEVFTTREFGDSSLIFAYDFHPLSKTLQEHHFQPAVPENTIWGYI
CQIANALKTIHSNRLAARCLEPSKIILTDINRIRLSACAILDVVQFGMNS
RSVVELQQEDFVKFGKLILSLATGTLPAHLNNIPAALETLGNKYSANLKS
AVNWLLDTSSGETKTIEHFMTGIASQMTTFFDLALQDNDEKLFHLAREVE
NGRIARSLMKLLTILERDRYQLKLFRDYVFHRVDADGKPNLSIGHMLTCM
SKLEAGVDENILLTSRDNETVFVLSYRELRQMYDRAFNELVKAS
3D structure
PDB4cyi Structural Basis for Pan3 Binding to Pan2 and its Function in Mrna Recruitment and Deadenylation
ChainE
Resolution2.42 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP E L256 N263 V273 A286 R288 H340 S343 K344 T345 S397 K398 L42 N49 V59 A72 R74 H126 S129 K130 T131 S173 K174
BS02 MG E D257 S271 D43 S57
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening
GO:0006397 mRNA processing
GO:0006468 protein phosphorylation
Cellular Component
GO:0031251 PAN complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4cyi, PDBe:4cyi, PDBj:4cyi
PDBsum4cyi
PubMed24872509
UniProtG0S0Y3|PAN3_CHATD PAN2-PAN3 deadenylation complex subunit PAN3 (Gene Name=PAN3)

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