Structure of PDB 4by9 Chain E

Receptor sequence
>4by9E (length=227) Species: 2261 (Pyrococcus furiosus) [Search protein sequence]
MVEVKKHKFPGVYVVIDDDGSEKIATKNLVPGQRVYGERVIKWEGEEYRI
WNPHRSKLGAAIVNGLKNFPIKPGKSVLYLGIASGTTASHVSDIVGWEGK
IYGIEFSPRVLRELVPIVEERRNIIPILGDATKPEEYRALVTKVDVIFED
VAQPTQAKILIDNAKAYLKRGGYGMIAVKSRSIDVTKEPEQVFKEVEREL
SEYFEVIERLNLEPYEKDHALFVVRKP
3D structure
PDB4by9 The Structure of the Box C/D Enzyme Reveals Regulation of RNA Methylation.
ChainE
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna E H54 S107 R109 Q153 P154 R181 V185 H54 S107 R109 Q153 P154 R181 V185
BS02 rna E R55 S56 K57 A83 S84 T86 T87 K179 R181 H219 R55 S56 K57 A83 S84 T86 T87 K179 R181 H219
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0008168 methyltransferase activity
GO:0008649 rRNA methyltransferase activity
GO:0016740 transferase activity
GO:1990259 histone H2AQ104 methyltransferase activity
Biological Process
GO:0000494 box C/D sno(s)RNA 3'-end processing
GO:0006338 chromatin remodeling
GO:0006364 rRNA processing
GO:0008033 tRNA processing
GO:0031167 rRNA methylation
GO:0032259 methylation
Cellular Component
GO:0031428 box C/D methylation guide snoRNP complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4by9, PDBe:4by9, PDBj:4by9
PDBsum4by9
PubMed24121435
UniProtQ8U4M2|FLPA_PYRFU Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase (Gene Name=flpA)

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