Structure of PDB 4bms Chain E

Receptor sequence
>4bmsE (length=247) Species: 517192 (Ralstonia sp. DSMZ 6428) [Search protein sequence]
YRLLNKTAVITGGNSGIGLATAKRFVAEGAYVFIVGRRRKELEQAAAEIG
RNVTAVKADVTKLEDLDRLYAIVREQRGSIDVLFANSGAIEQKTLEEITP
EHYDRTFDVNVRGLIFTVQKALPLLRDGGSVILTSSVAGVLGLQAHDTYS
AAKAAVRSLARTWTTELKGRSIRVNAVSPGAIDTPIIENVSTQEEADELR
AKFAAATPLGRVGRPEELAAAVLFLASDDSSYVAGIELFVDGGLTQV
3D structure
PDB4bms Structures of Alcohol Dehydrogenases from Ralstonia and Sphingobium Spp. Reveal the Molecular Basis for Their Recognition of 'Bulky-Bulky' Ketones
ChainE
Resolution2.89 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S137 H147 Y150 K154 Q195
Catalytic site (residue number reindexed from 1) S136 H146 Y149 K153 Q193
Enzyme Commision number 1.1.1.1: alcohol dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAP E G13 N15 S16 R38 R39 D60 V61 N87 S88 G89 V110 S137 Y150 K154 G181 I183 T185 I187 G12 N14 S15 R37 R38 D59 V60 N86 S87 G88 V109 S136 Y149 K153 G180 I182 T184 I186
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016491 oxidoreductase activity
GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor

View graph for
Molecular Function
External links
PDB RCSB:4bms, PDBe:4bms, PDBj:4bms
PDBsum4bms
PubMed
UniProtC0IR58

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