Structure of PDB 4b0i Chain E

Receptor sequence
>4b0iE (length=167) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence]
KQHAFTREDLLRCSRGELFGPGNAQLPAPNMLMIDRIVHISDVGGKYGKG
ELVAELDINPDLWFFACNFEGDPVMPGCLGLDAMWQLVGFYLGWQGNPGR
GRALGSGEVKFFGQVLPTAKKVTYNIHIKRTINLVLAIADGTVSVDGREI
YSAEGLRVGLFTSTDSF
3D structure
PDB4b0i Structural Insights Into the Mechanism and Inhibition of the Beta-Hydroxydecanoyl-Acyl Carrier Protein Dehydratase from Pseudomonas Aeruginosa
ChainE
Resolution2.03 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) N70 V76 G79 C80 D84
Catalytic site (residue number reindexed from 1) N68 V74 G77 C78 D82
Enzyme Commision number 4.2.1.59: 3-hydroxyacyl-[acyl-carrier-protein] dehydratase.
5.3.3.14: trans-2-decenoyl-[acyl-carrier-protein] isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 KBP E F71 G79 G115 Q116 F69 G77 G113 Q114
Gene Ontology
Molecular Function
GO:0016829 lyase activity
GO:0016853 isomerase activity
GO:0019171 (3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
GO:0034017 trans-2-decenoyl-acyl-carrier-protein isomerase activity
Biological Process
GO:0006633 fatty acid biosynthetic process
GO:0006636 unsaturated fatty acid biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Biological Process
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Cellular Component
External links
PDB RCSB:4b0i, PDBe:4b0i, PDBj:4b0i
PDBsum4b0i
PubMed23174186
UniProtO33877|FABA_PSEAE 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase (Gene Name=fabA)

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