Structure of PDB 4a76 Chain E

Receptor sequence
>4a76E (length=87) Species: 8364 (Xenopus tropicalis) [Search protein sequence]
DPQVLRGSGHCKWFNVRMGFGFISMTSREGSPLENPVDVFVHQSKLYMEG
FRSLKEGEPVEFTFKKSSKGFESLRVTGPGGNPCLGN
3D structure
PDB4a76 The Lin28 Cold-Shock Domain Remodels Pre-Let-7 Microrna.
ChainE
Resolution1.92 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna E V42 R43 G45 Q69 F77 R78 V16 R17 G19 Q43 F51 R52 PDBbind-CN: Kd=59nM
BS02 dna E W39 N41 M44 F48 D64 F66 H68 S93 K95 W13 N15 M18 F22 D38 F40 H42 S67 K69 PDBbind-CN: Kd=59nM
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding

View graph for
Molecular Function
External links
PDB RCSB:4a76, PDBe:4a76, PDBj:4a76
PDBsum4a76
PubMed22570413
UniProtB4F6I0

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