Structure of PDB 3zqj Chain E

Receptor sequence
>3zqjE (length=919) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
ADRLIVKGAREHNLRSVDLDLPRDALIVFTGLSGSGKSSLAFDTIFAEGQ
RRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVSIDQKSTNRNPRSTVGT
ITEVYDYLRLLYARAGTPHCPARQTPQQIVDQVLAMPEGTRFLVLAPVVR
TRKGEFADLFDKLNAQGYSRVRVDGVVHPLTDPPKLKKQEKHDIEVVVDK
RRLTDSVETALNLADGIVVLEFVDHLACPNGHALAVDDLEPRSFSFNSPY
GACPECSGLGIRKEVDPELVVPDPDRTLAQGAVAPWSNGHTAEYFTRMMA
GLGEALGFDVDTPWLPAKARKAILEGADEQVHVRYRNRYGRTRSYYADFE
GVLAFLQRKMSQTESEQMKERYEGFMRDVPCPVCAGTRLKPEILAVTLAK
GEHGAKSIAEVCELSIADCADFLNALTLGPREQAIAGQVLKEIRSRLGFL
LDVGLEYLSLSRAAATLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLH
QRDNRRLIETLTRLRDLGNTLIVVEHDEDTIEHADWIVDIGPGAGEHGGR
IVHSGPYDELLRNKDSITGAYLSGRESIEIPAIRRSVDPRRQLTVVGARE
HNLRGIDVSFPLGVLTSVTGVSGSGKSTLVNDILAAVLANRLNGARQVPG
RHTRVTGLDYLDKLVRVDQSPIGRTPRSNPATYTGVFDKIRTLFAATTEA
KVRGYQPGRFSFNVKGGRCEACTGDGTIKIEMNFLPDVYVPCEVCQGARY
NRETLEVHYKGKTVSEVLDMSIEEAAEFFEPIAGVHRYLRTLVDVGLGYV
RLGQPAPTLSGGEAQRVKLASELQKRSTGRTVYILDEPTTGLHFDDIRKL
LNVINGLVDKGNTVIVIEHNLDVIKTSDWIIDLGPEGGAGGGTVVAQGTP
EDVAAVPASYTGKFLAEVV
3D structure
PDB3zqj The Biological and Structural Characterization of Mycobacterium Tuberculosis Uvra Provides Novel Insights Into its Mechanism of Action
ChainE
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN E C753 C756 C776 C779 C719 C722 C742 C745
BS02 ZN E C285 C412 C415 C256 C381 C384
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004518 nuclease activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008270 zinc ion binding
GO:0009381 excinuclease ABC activity
GO:0016887 ATP hydrolysis activity
GO:0046872 metal ion binding
Biological Process
GO:0006281 DNA repair
GO:0006289 nucleotide-excision repair
GO:0006974 DNA damage response
GO:0009432 SOS response
GO:0060543 negative regulation of strand invasion
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0009274 peptidoglycan-based cell wall
GO:0009380 excinuclease repair complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3zqj, PDBe:3zqj, PDBj:3zqj
PDBsum3zqj
PubMed21622956
UniProtP9WQK7|UVRA_MYCTU UvrABC system protein A (Gene Name=uvrA)

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