Structure of PDB 3v83 Chain E

Receptor sequence
>3v83E (length=674) Species: 9606 (Homo sapiens) [Search protein sequence]
KTVRWCAVSEHEATKCQSFRDHMKSVIPSDGPSVACVKKASYLDCIRAIA
ANEADAVTLDAGLVYDAYLAPNNLKPVVAEFYGSKEDPQTFYYAVAVVKK
DSGFQMNQLRGKKSCHTGLGRSAGWNIPIGLLYCDLPEPRKPLEKAVANF
FSGSCAPCADGTDFPQLCQLCPGCGCSTLNQYFGYSGAFKCLKDGAGDVA
FVKHSTIFENLANKADRDQYELLCLDNTRKPVDEYKDCHLAQVPSHTVVA
RSMGGKEDLIWELLNQAQEHFGKDKSKEFQLFSSPHGKDLLFKDSAHGFL
KVPPRMDAKMYLGYEYVTAIRNLREGTCPEAPTDECKPVKWCALSHHERL
KCDEWSVNSVGKIECVSAETTEDCIAKIMNGEADAMSLDGGFVYIAGKCG
LVPVLAENYNKSDNCEDTPEAGYFAVAVVKKSASDLTWDNLKGKKSCHTA
VGRTAGWNIPMGLLYNKINHCRFDEFFSEGCAPGSKKDSSLCKLCMGSGL
NLCEPNNKEGYYGYTGAFRCLVEKGDVAFVKHQTVPQNTGGKNPDPWAKN
LNEKDYELLCLDGTRKPVEEYANCHLARAPNHAVVTRKDKEACVHKILRQ
QQHLFGSNVTDCSGNFCLFRSETKDLLFRDDTVCLAKLHDRNTYEKYLGE
EYVKAVGNLRKCSTSSLLEACTFR
3D structure
PDB3v83 Structural basis for iron piracy by pathogenic Neisseria.
ChainE
Resolution2.102 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BCT E D63 T120 R124 S125 A126 G127 Y188 D60 T117 R121 S122 A123 G124 Y185
BS02 BCT E D392 T452 R456 T457 A458 Y517 D389 T449 R453 T454 A455 Y514
BS03 FE E D63 Y95 Y188 H249 D60 Y92 Y185 H246
BS04 FE E D392 Y426 Y517 H585 D389 Y423 Y514 H582
Gene Ontology
Molecular Function
GO:0008199 ferric iron binding
Biological Process
GO:0006826 iron ion transport
GO:0006879 intracellular iron ion homeostasis
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3v83, PDBe:3v83, PDBj:3v83
PDBsum3v83
PubMed22327295
UniProtP02787|TRFE_HUMAN Serotransferrin (Gene Name=TF)

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