Structure of PDB 3sl9 Chain E

Receptor sequence
>3sl9E (length=165) Species: 9606 (Homo sapiens) [Search protein sequence]
NYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMR
SPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPAL
VKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTN
VKFLAITTDCLQILA
3D structure
PDB3sl9 An intrinsically labile alpha-helix abutting the BCL9-binding site of beta-catenin is required for its inhibition by carnosic acid.
ChainE
Resolution2.2 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide E Q203 N204 T205 N206 K242 M243 G245 S246 K281 Q63 N64 T65 N66 K102 M103 G105 S106 K141
BS02 peptide E E155 L159 D162 D164 V166 V167 K170 M174 L178 E15 L19 D22 D24 V26 V27 K30 M34 L38
Gene Ontology
Molecular Function
GO:0045296 cadherin binding
Biological Process
GO:0007155 cell adhesion

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:3sl9, PDBe:3sl9, PDBj:3sl9
PDBsum3sl9
PubMed22353711
UniProtP35222|CTNB1_HUMAN Catenin beta-1 (Gene Name=CTNNB1)

[Back to BioLiP]