Structure of PDB 3sh1 Chain E

Receptor sequence
>3sh1E (length=215) Species: 6500 (Aplysia californica) [Search protein sequence]
KDDDDKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVYLSFSLLDIVKA
DSSTNEVDLVYWEQQSWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAY
SSTRPVQVLSPQNALVNSSGHVQYLPAQRLSFMCDPTGVDSEEGATCAVK
FGSWSYGGWEIDLKTDTDQVDLSSYYASSKYEILSATQTRSERFYECCKE
PYPDVNLVVKFRERR
3D structure
PDB3sh1 Creating an alpha-7 nicotinic acetylcholine recognition domain from the acetylcholine binding protein: crystallographic and ligand selectivity analyses
ChainE
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MLK E W55 L118 S167 W62 L125 S174 PDBbind-CN: -logKd/Ki=7.39,Ki=41nM
BS02 MG E D-3 H1 D4 H8
BS03 MLK E Y93 K143 W147 Y149 R186 Y188 Y195 D197 Y100 K150 W154 Y156 R193 Y195 Y202 D204 PDBbind-CN: -logKd/Ki=7.39,Ki=41nM
Gene Ontology
Molecular Function
GO:0004888 transmembrane signaling receptor activity
GO:0005216 monoatomic ion channel activity
GO:0005230 extracellular ligand-gated monoatomic ion channel activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0034220 monoatomic ion transmembrane transport
Cellular Component
GO:0016020 membrane

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Cellular Component
External links
PDB RCSB:3sh1, PDBe:3sh1, PDBj:3sh1
PDBsum3sh1
PubMed22009746
UniProtQ8WSF8

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