Structure of PDB 3s4s Chain E

Receptor sequence
>3s4sE (length=185) Species: 9606 (Homo sapiens) [Search protein sequence]
MGDTRPRFLWQLKFECHFFNGTERVRLLERCIYNQEESVRFDSDVGEYRA
VTELGRPDAEYWNSQKDLLEQRRAAVDTYCRHNYGVGESFTVQRRVEPKV
TVYPSKHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTF
QTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRA
3D structure
PDB3s4s Affinity maturation of human CD4 by yeast surface display and crystal structure of a CD4-HLA-DR1 complex.
ChainE
Resolution2.4 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide E F13 Y47 P56 D57 W61 R71 Y78 H81 N82 V85 F14 Y48 P57 D58 W62 R72 Y79 H82 N83 V86
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3s4s, PDBe:3s4s, PDBj:3s4s
PDBsum3s4s
PubMed21900604
UniProtP01911|DRB1_HUMAN HLA class II histocompatibility antigen, DRB1 beta chain (Gene Name=HLA-DRB1)

[Back to BioLiP]