Structure of PDB 3qa3 Chain E

Receptor sequence

>3qa3E (length=186) Species: 9606 (Homo sapiens) [Search protein sequence]

DSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQLKKSKTLFSLMQYSEEFR
IHFTFKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNGARK
NAFKILVVITDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRSEKSR
QELNTIASKPPRDHVFQVNNFEALKTIQNQLREKGF

3D structure

PDB

3qa3 Stable Coordination of the Inhibitory Ca2+ Ion at the Metal Ion-Dependent Adhesion Site in Integrin CD11b/CD18 by an Antibody-Derived Ligand Aspartate: Implications for Integrin Regulation and Structure-Based Drug Design.

Chain

Resolution

3.0 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	CA	E	S142 S144 D242	S11 S13 D111

External links

PDB	RCSB:3qa3, PDBe:3qa3, PDBj:3qa3
PDBsum	3qa3
PubMed	22095715
UniProt	P11215\|ITAM_HUMAN Integrin alpha-M (Gene Name=ITGAM)

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