Structure of PDB 3pla Chain E

Receptor sequence
>3plaE (length=227) Species: 2287 (Saccharolobus solfataricus) [Search protein sequence]
ITVKQTNMENIYECEFNDGSFRLCTRNLVPNFNVYGERLIKYEGVEYREW
NAFRSKLAGAILKGLKTNPIRKGTKVLYLGAASGTTISHVSDIIELNGKA
YGVEFSPRVVRELLLVAQRRPNIFPLLADARFPQSYKSVVENVDVLYVDI
AQPDQTDIAIYNAKFFLKVNGDMLLVIKARSIDVTKDPKEIYKTEVEKLE
NSNFETIQIINLDPYDKDHAIVLSKYK
3D structure
PDB3pla Structural basis for site-specific ribose methylation by box C/D RNA protein complexes.
ChainE
Resolution3.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna E S110 R112 A155 P157 R184 S185 D187 V188 S106 R108 A151 P153 R180 S181 D183 V184
BS02 rna E R58 K60 S87 T89 D220 K221 H223 R54 K56 S83 T85 D216 K217 H219
BS03 SAH E Y82 G84 A86 T90 E108 F109 A134 D153 A155 Q156 Y78 G80 A82 T86 E104 F105 A130 D149 A151 Q152
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0008168 methyltransferase activity
GO:0008649 rRNA methyltransferase activity
GO:0016740 transferase activity
GO:1990259 histone H2AQ104 methyltransferase activity
Biological Process
GO:0000494 box C/D sno(s)RNA 3'-end processing
GO:0006338 chromatin remodeling
GO:0006364 rRNA processing
GO:0008033 tRNA processing
GO:0031167 rRNA methylation
GO:0032259 methylation
Cellular Component
GO:0031428 box C/D methylation guide snoRNP complex

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Cellular Component
External links
PDB RCSB:3pla, PDBe:3pla, PDBj:3pla
PDBsum3pla
PubMed21270896
UniProtP58032|FLPA_SACS2 Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase (Gene Name=flpA)

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