Structure of PDB 3pgc Chain E

Receptor sequence
>3pgcE (length=180) Species: 9606 (Homo sapiens) [Search protein sequence]
DTRPRFLWQLKFECHFFNGTERVRLLERCIYNQEESVRFDSDVGEYRAVT
ELGRPDAEYWNSQKDLLEQRRAAVDTYCRHNYGVGESFTVQRRVEPKVTV
YPSNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLV
MLETVPRSGEVYTCQVEHPSVTSPLTVEWR
3D structure
PDB3pgc Bidirectional binding of invariant chain peptides to an MHC class II molecule.
ChainE
Resolution2.66 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide E W9 F13 Y47 D57 Y60 W61 L67 R71 Y78 H81 N82 V85 W8 F12 Y46 D56 Y59 W60 L66 R70 Y77 H80 N81 V84
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process
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Cellular Component
External links
PDB RCSB:3pgc, PDBe:3pgc, PDBj:3pgc
PDBsum3pgc
PubMed21115828
UniProtP01911|DRB1_HUMAN HLA class II histocompatibility antigen, DRB1 beta chain (Gene Name=HLA-DRB1)

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