Structure of PDB 3ozb Chain E

Receptor sequence
>3ozbE (length=236) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence]
VYAIIGGTGLTQLEGLTLSESLPIETPYGAPSAPLQRGRYAGREVLFLAR
HPPHQVNYRANLWALKQAGAEAVIAVNAVGGIHAAMGTGHLCVPHQLIDY
TSGREHTYFAGDIEHVTHIDFSHPYDEPLRQRLIEALRALGLAHSSHGVY
ACTQGPRLETVAEIARLERDGNDIVGMTGMPEAALARELDLPYACLALVV
NPAAGKSAGIITMAEIEQALHDGIGKVREVLARVLA
3D structure
PDB3ozb Methylthioinosine phosphorylase from Pseudomonas aeruginosa. Structure and annotation of a novel enzyme in quorum sensing.
ChainE
Resolution2.8 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) T24 P47 P74 A100 M199 T200 N223 A225 M235
Catalytic site (residue number reindexed from 1) T8 P31 P52 A78 M177 T178 N201 A203 M213
Enzyme Commision number 2.4.2.44: S-methyl-5'-thioinosine phosphorylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HPA E V101 G102 E181 V197 N223 V79 G80 E159 V175 N201
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0016757 glycosyltransferase activity
GO:0016763 pentosyltransferase activity
GO:0017061 S-methyl-5-thioadenosine phosphorylase activity
Biological Process
GO:0006166 purine ribonucleoside salvage
GO:0009116 nucleoside metabolic process
GO:0019509 L-methionine salvage from methylthioadenosine
Cellular Component
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3ozb, PDBe:3ozb, PDBj:3ozb
PDBsum3ozb
PubMed21197954
UniProtQ9HZK1|MTIP_PSEAE S-methyl-5'-thioinosine phosphorylase (Gene Name=PA3004)

[Back to BioLiP]