Structure of PDB 3n84 Chain E

Receptor sequence
>3n84E (length=102) Species: 9606 (Homo sapiens) [Search protein sequence]
MIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKF
GNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDI
EQ
3D structure
PDB3n84 Thermodynamic and Structural Effects of Macrocyclization as a Constraining Method in Protein-Ligand Interactions.
ChainE
Resolution2.0 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide E R67 R86 S88 S90 S96 Q106 H107 F108 K109 L120 W121 R16 R35 S37 S39 S45 Q55 H56 F57 K58 L69 W70
External links
PDB RCSB:3n84, PDBe:3n84, PDBj:3n84
PDBsum3n84
PubMed21116482
UniProtP62993|GRB2_HUMAN Growth factor receptor-bound protein 2 (Gene Name=GRB2)

[Back to BioLiP]