Structure of PDB 3mq6 Chain E

Receptor sequence
>3mq6E (length=333) Species: 1911 (Streptomyces griseus) [Search protein sequence]
PFTYSIEATRNLATTERCIQDIRNRSTQFQLAQQNMLAYTFGEVIPGFAS
AGINGMDYRDVIGRPVENAVTEGTHFFRDDFRVDSNAKAKVAGDIFEIVS
SAVMWNCAARWNSLMVGEGWRSQPRYSRPTLSPSPRRQVAVLNLPRSFDW
VSLLVPESQEVIEEFRAGLRKDGLGLPTSTPDLAVVVLPEEFQNDEMWRE
EIAGLTRPNQILLSGAYQRLQGRVQPGEISLAVAFKRSLRSDRLYQPLYE
ANVMQLLLEGKLGAPKVEFEVHTLAPEGTNAFVTYEAASLYGLAEGRSAV
HRAIRELYVPPTAADLARRFFAFLNERMELVNG
3D structure
PDB3mq6 Domain swapping in allosteric modulation of DNA specificity.
ChainE
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna E R31 T33 Q36 L37 Q39 Q40 N92 A93 K96 R152 R246 S247 D248 R25 T27 Q30 L31 Q33 Q34 N86 A87 K90 R146 R240 S241 D242 PDBbind-CN: Kd=0.6nM
BS02 dna E A95 K96 G99 R152 S153 K242 R243 S244 R246 R249 A89 K90 G93 R146 S147 K236 R237 S238 R240 R243 PDBbind-CN: Kd=0.6nM
BS03 CA E D188 F241 D182 F235
BS04 CA E E103 N149 L150 E97 N143 L144
Gene Ontology
Molecular Function
GO:0042802 identical protein binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:3mq6, PDBe:3mq6, PDBj:3mq6
PDBsum3mq6
PubMed21151881
UniProtQ9F6L0

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