Structure of PDB 3mbe Chain E

Receptor sequence
>3mbeE (length=184) Species: 10090 (Mus musculus) [Search protein sequence]
DIEADHVGFYGTTVYQSPGDIGQYTHEFDGDELFYVDLDKKKTVWRLPEF
GQLILFEPQGGLQNIAAEKHNLGILTKRSNFTPATNEAPQATVFPKSPVL
LGQPNTLICFVDNIFPPVINITWLRNSKSVTDGVYETSFLVNRDHSFHKL
SYLTFIPSDDDIYDCKVEHWGLEEPVLKHWSSAD
3D structure
PDB3mbe The diabetogenic mouse MHC class II molecule I-Ag7 is endowed with a switch that modulates TCR affinity.
ChainE
Resolution2.886 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide E I52 L53 N62 A65 E66 H68 N69 I72 I54 L55 N64 A67 E68 H70 N71 I74
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process
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Cellular Component
External links
PDB RCSB:3mbe, PDBe:3mbe, PDBj:3mbe
PDBsum3mbe
PubMed20407212
UniProtP04228|HA2D_MOUSE H-2 class II histocompatibility antigen, A-D alpha chain (Gene Name=H2-Aa)

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