Structure of PDB 3m3k Chain E

Receptor sequence
>3m3kE (length=258) Species: 10116 (Rattus norvegicus) [Search protein sequence]
RTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKL
SIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFS
KPFMSLGISIMIKKGTPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIA
VYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLESTMNEYIEQR
KPCDTMKVGGNLDSKGYGVATPKGSALGNAVNLAVLKLNEQGLLDKLKNK
WWYDKGEC
3D structure
PDB3m3k Molecular mechanism of flop selectivity and subsite recognition for an AMPA receptor allosteric modulator: structures of GluA2 and GluA3 in complexes with PEPA.
ChainE
Resolution1.793 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GLU E Y61 L90 T91 R96 L138 G141 S142 T143 E193 Y58 L87 T88 R93 L135 G138 S139 T140 E190
BS02 ZN E E42 H46 E39 H43
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:3m3k, PDBe:3m3k, PDBj:3m3k
PDBsum3m3k
PubMed20199107
UniProtP19492|GRIA3_RAT Glutamate receptor 3 (Gene Name=Gria3)

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