Structure of PDB 3lo5 Chain E

Receptor sequence
>3lo5E (length=151) Species: 9606 (Homo sapiens) [Search protein sequence]
MTEYKLVVVGAGGVGKNALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGET
CLLDILMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVG
NKCDLAARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQ
H
3D structure
PDB3lo5 Structure of the Dominant Negative S17N Mutant of Ras
ChainE
Resolution2.568 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GDP E G13 G15 K16 N17 A18 F28 D30 N116 K117 D119 S145 A146 K147 G13 G15 K16 N17 A18 F28 D30 N101 K102 D104 S130 A131 K132
BS02 CA E D30 E31 D30 E31
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0007165 signal transduction
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3lo5, PDBe:3lo5, PDBj:3lo5
PDBsum3lo5
PubMed20131908
UniProtP01112|RASH_HUMAN GTPase HRas (Gene Name=HRAS)

[Back to BioLiP]