Structure of PDB 3l25 Chain E

Receptor sequence
>3l25E (length=123) Species: 128952 (Ebola virus - Mayinga, Zaire, 1976) [Search protein sequence]
DISAKDLRNIMYDHLPGFGTAFHQLVQVICKLGKDSNSLDIIHAEFQASL
AEGDSPQCALIQITKRVPIFQDAAPPVIHIRSRGDIPRACQKSLRPVPPS
PKIDRGWVCVFQLQDGKTLGLKI
3D structure
PDB3l25 Structural basis for dsRNA recognition and interferon antagonism by Ebola VP35.
ChainE
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna E F239 Q274 I340 F22 Q57 I123 PDBbind-CN: Kd=500nM
BS02 rna E I278 Q279 K282 R312 R322 I61 Q62 K65 R95 R105 PDBbind-CN: Kd=500nM
External links
PDB RCSB:3l25, PDBe:3l25, PDBj:3l25
PDBsum3l25
PubMed20081868
UniProtQ05127|VP35_EBOZM Polymerase cofactor VP35 (Gene Name=VP35)

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