Structure of PDB 3hus Chain E

Receptor sequence
>3husE (length=303) Species: 9606 (Homo sapiens) [Search protein sequence]
TVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPV
VSGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNR
QDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRM
GPTELLIEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMD
GASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYN
RCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKMSMKIR
PFF
3D structure
PDB3hus Impaired protofibril formation in fibrinogen gammaN308K is due to altered D:D and "A:a" interactions.
ChainE
Resolution3.04 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide E L360 W385 E397 D398 R406 C407 H408 T431 D432 L205 W230 E242 D243 R251 C252 H253 T276 D277
BS02 CA E D381 W385 D226 W230
Gene Ontology
Molecular Function
GO:0005102 signaling receptor binding
Biological Process
GO:0007596 blood coagulation
GO:0030168 platelet activation
GO:0051258 protein polymerization
Cellular Component
GO:0005577 fibrinogen complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3hus, PDBe:3hus, PDBj:3hus
PDBsum3hus
PubMed19650644
UniProtP02675|FIBB_HUMAN Fibrinogen beta chain (Gene Name=FGB)

[Back to BioLiP]