Structure of PDB 3g71 Chain E

Receptor sequence

>3g71E (length=172) Species: 2238 (Haloarcula marismortui) [Search protein sequence]

PRVELEIPEDVDAEQDHLDITVEGDNGSVTRRLWYPDIDVSVDGDTVVIE
SDEDNAKTMSTIGTFQSHIENMFHGVTEGWEYGMEVFYSHFPMQVNVEGD
EVVIENFLGEKAPRRTTIHGDTDVEIDGEELTVSGPDIEAVGQTAADIEQ
LTRINDKDVRVFQDGVYITRKP

3D structure

PDB

3g71 U2504 determines the species specificity of the A-site cleft antibiotics: the structures of tiamulin, homoharringtonine, and bruceantin bound to the ribosome.

Chain

Resolution

2.85 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	E	Y35 N55 A56 S60 G63 T64 S67 H68 N71 Y82 H90 F91 G109 E110 K111 A112 H119 E139 G142 Q143 A146 Q150 R153 K157 D158 R160 V161 F162	Y35 N55 A56 S60 G63 T64 S67 H68 N71 Y82 H90 F91 G109 E110 K111 A112 H119 E139 G142 Q143 A146 Q150 R153 K157 D158 R160 V161 F162

Gene Ontology

	Molecular Function
GO:0003735	structural constituent of ribosome
GO:0019843	rRNA binding

	Biological Process
GO:0002181	cytoplasmic translation
GO:0006412	translation

	Cellular Component
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:3g71, PDBe:3g71, PDBj:3g71
PDBsum	3g71
PubMed	19362093
UniProt	P14135\|RL6_HALMA Large ribosomal subunit protein uL6 (Gene Name=rpl6)

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