Structure of PDB 3fhz Chain E

Receptor sequence
>3fhzE (length=155) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
ANRAGRQARIVAILSSAQVRSQNELAALLAAEGIEVTQATLSRDLEELGA
VKLRGADGGTGIYVVPEDGSPVRGVSGGTDRMARLLGELLVSTDDSGNLA
VLRTPPGAAHYLASAIDRAALPQVVGTIAGDDTILVVAREPTTGAQLAGM
FENLR
3D structure
PDB3fhz The structure of the arginine repressor from Mycobacterium tuberculosis bound with its DNA operator and Co-repressor, L-arginine.
ChainE
Resolution3.27 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna E S36 Q37 Q53 S57 R58 Y78 S21 Q22 Q38 S42 R43 Y63
BS02 dna E R18 R21 T52 A54 T55 R58 R3 R6 T37 A39 T40 R43
BS03 ARG E G145 D146 D147 T148 G130 D131 D132 T133
BS04 ARG E D132 T142 I143 A144 D117 T127 I128 A129
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0034618 arginine binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006525 arginine metabolic process
GO:0006526 L-arginine biosynthetic process
GO:0051259 protein complex oligomerization
GO:1900079 regulation of arginine biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:3fhz, PDBe:3fhz, PDBj:3fhz
PDBsum3fhz
PubMed19265706
UniProtP9WPY9|ARGR_MYCTU Arginine repressor (Gene Name=argR)

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