Structure of PDB 3e1i Chain E

Receptor sequence
>3e1iE (length=298) Species: 9606 (Homo sapiens) [Search protein sequence]
IPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKE
CEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSV
DFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTEL
LIEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQL
MGENRTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAA
NPNGRYYWGGQYTWDMAKHGTADGVVWMNWKGSWYSMRKMSMKIRPFF
3D structure
PDB3e1i Fibrinogen variant BbetaD432A has normal polymerization but does not bind knob "B".
ChainE
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA E D381 D383 W385 D221 D223 W225
BS02 CA E D261 G263 D398 D101 G103 D238
Gene Ontology
Molecular Function
GO:0005102 signaling receptor binding
Biological Process
GO:0007596 blood coagulation
GO:0030168 platelet activation
GO:0051258 protein polymerization
Cellular Component
GO:0005577 fibrinogen complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3e1i, PDBe:3e1i, PDBj:3e1i
PDBsum3e1i
PubMed19075185
UniProtP02675|FIBB_HUMAN Fibrinogen beta chain (Gene Name=FGB)

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