Structure of PDB 3dab Chain E

Receptor sequence
>3dabE (length=86) Species: 9606 (Homo sapiens) [Search protein sequence]
IQINQVRPKLPLLKILHAAGAQGEMFTVKEVMHYLGQYIMVKQLYDQQEQ
HMVYCGGDLLGELLGRQSFSVKDPSPLYDMLRKNLV
3D structure
PDB3dab Structure of the human Mdmx protein bound to the p53 tumor suppressor transactivation domain.
ChainE
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide E M53 G57 I60 Y66 E70 Q71 H72 V92 K93 P95 M32 G36 I39 Y45 E49 Q50 H51 V71 K72 P74
Gene Ontology
Biological Process
GO:0043066 negative regulation of apoptotic process
GO:0051726 regulation of cell cycle
Cellular Component
GO:0005634 nucleus

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Biological Process
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Cellular Component
External links
PDB RCSB:3dab, PDBe:3dab, PDBj:3dab
PDBsum3dab
PubMed18677113
UniProtO15151|MDM4_HUMAN Protein Mdm4 (Gene Name=MDM4)

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