Structure of PDB 3d47 Chain E

Receptor sequence

>3d47E (length=405) Species: 99287 (Salmonella enterica subsp. enterica serovar Typhimurium str. LT2)

MENIMTLPKIKHVRAWFIGGATAEKGAGGGDYHDQGGNHWIDDHIATPMS
KYRDYEQSRQSFGINVLGTLIVEVEAENRQTGFAVSTAGEMGCFIVEKHL
NRFIEGKCVSDIKLIHDQMLGATMYYSGSGGLVMNTISCVDLALWDLFGK
VVGLPVYKLLGGAVRDEIQFYATGARPDLAKEMGFIGGKMPTHWGPHDGD
AGIRKDAAMVADMREKCGPDFWLMLDCWMSQDVNYATKLAHACAPFNLKW
IEECLPPQQYEGYRELKRNAPAGMMVTSGEHHGTLQSFRTLAETGIDIMQ
PDVGWCGGLTTLVEIAALAKSRGQLVVPHGSSVYSHHAVITFTNTPFSEF
LMTSPDCSTLRPQFDPILLDEPVPVNGRIHKSVLDKPGFGVELNRDCHLK
RPYSH

3D structure

• PDB: 3d47 Crystal structure of L-rhamnonate dehydratase from Salmonella typhimurium complexed with Mg and D-malate.
• Chain: E
• Resolution: 1.8 Å

Enzymatic activity

• Catalytic site (original residue number in PDB): K189 P191 G195 H197 A201 D226 W228 E252 T277 E280 Q300 D302 H329 E349 P362
• Catalytic site (residue number reindexed from 1): K189 P191 G195 H197 A201 D226 W228 E252 T277 E280 Q300 D302 H329 E349 P362
• Enzyme Commision number: 4.2.1.90: L-rhamnonate dehydratase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	MG	E	D226 E252 E280	D226 E252 E280

Gene Ontology

Molecular Function

• GO:0000287 magnesium ion binding
• GO:0016829 lyase activity
• GO:0016836 hydro-lyase activity
• GO:0046872 metal ion binding
• GO:0050032 L-rhamnonate dehydratase activity

Biological Process

• GO:0009063 amino acid catabolic process
• GO:0016052 carbohydrate catabolic process

External links

• PDB: RCSB:3d47, PDBe:3d47, PDBj:3d47
• PDBsum: 3d47
• UniProt: Q8ZNF9|RHMD_SALTY L-rhamnonate dehydratase (Gene Name=rhmD)