Structure of PDB 3cxc Chain E

Receptor sequence
>3cxcE (length=172) Species: 2238 (Haloarcula marismortui) [Search protein sequence]
PRVELEIPEDVDAEQDHLDITVEGDNGSVTRRLWYPDIDVSVDGDTVVIE
SDEDNAKTMSTIGTFQSHIENMFHGVTEGWEYGMEVFYSHFPMQVNVEGD
EVVIENFLGEKAPRRTTIHGDTDVEIDGEELTVSGPDIEAVGQTAADIEQ
LTRINDKDVRVFQDGVYITRKP
3D structure
PDB3cxc Design at the atomic level: design of biaryloxazolidinones as potent orally active antibiotics.
ChainE
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna E Y35 N55 S60 G63 T64 S67 H68 N71 Y82 H90 F91 E110 K111 A112 H119 E139 Q143 A146 Q150 R153 N155 K157 D158 R160 V161 F162 Y35 N55 S60 G63 T64 S67 H68 N71 Y82 H90 F91 E110 K111 A112 H119 E139 Q143 A146 Q150 R153 N155 K157 D158 R160 V161 F162 PDBbind-CN: IC50=4.6uM
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Cellular Component
External links
PDB RCSB:3cxc, PDBe:3cxc, PDBj:3cxc
PDBsum3cxc
PubMed18947996
UniProtP14135|RL6_HALMA Large ribosomal subunit protein uL6 (Gene Name=rpl6)

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