Structure of PDB 3ab2 Chain E

Receptor sequence
>3ab2E (length=383) Species: 1718 (Corynebacterium glutamicum) [Search protein sequence]
ALVVQKYGGSSLESAERIRNVAERIVATKKAGNDVVVVCSAMGDTTDELL
ELAAAVNPVPPAREMDMLLTAGERISNALVAMAIESLGAEAQSFTGSQAG
VLTVTPGRVREALDEGKICIVAGFQRGGSDTTAVALAAALNADVCEIYSD
VDGVYTADPRIVPNAQKLEKLSFEEMLELAAVGSKILVLRSVEYARAFNV
PLRVRSSYSNDPGTLIAGSMEDIPVEEAVLTGVATDKSEAKVTVLGISDK
PGEAAKVFRALADAEINIDMVLQNVSSVEDGTTDITFTCPRSDGRRAMEI
LKKLQVQGNWTNVLYDDQVGKVSLVGAGMKSHPGVTAEFMEALRDVNVNI
ELISTSEIRISVLIREDDLDAAARALHEQFQLG
3D structure
PDB3ab2 Mechanism of concerted inhibition of {alpha}2{beta}2-type heterooligomeric aspartate kinase from Corynebacterium glutamicum
ChainE
Resolution2.59 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.2.4: aspartate kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 THR E D274 K275 G277 E278 A279 Q298 D249 K250 G252 E253 A254 Q273
BS02 THR E N374 I375 N349 I350
Gene Ontology
Molecular Function
GO:0004072 aspartate kinase activity
GO:0005524 ATP binding
GO:0016301 kinase activity
Biological Process
GO:0008652 amino acid biosynthetic process
GO:0009085 lysine biosynthetic process
GO:0009088 threonine biosynthetic process
GO:0009089 lysine biosynthetic process via diaminopimelate
GO:0009090 homoserine biosynthetic process
GO:0016310 phosphorylation
GO:0019877 diaminopimelate biosynthetic process
Cellular Component
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3ab2, PDBe:3ab2, PDBj:3ab2
PDBsum3ab2
PubMed20573952
UniProtP26512|AK_CORGL Aspartokinase (Gene Name=lysC)

[Back to BioLiP]