Structure of PDB 2wat Chain E

Receptor sequence
>2watE (length=120) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
GGVGVDVELITSINVENDTFIERNFTPQEIEYCSAQPSVQSSFAGTWSAK
EAVFKSLGVKSLGGGAALKDIEIVRVNKNAPAVELHGNAKKAAEEAGVTD
VKVSISHDDLQAVAVAVSTK
3D structure
PDB2wat Multimeric Options for the Auto-Activation of the Saccharomyces Cerevisiae Fas Type I Megasynthase.
ChainE
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.100: 3-oxoacyl-[acyl-carrier-protein] reductase.
2.3.1.41: beta-ketoacyl-[acyl-carrier-protein] synthase I.
2.3.1.86: fatty-acyl-CoA synthase system.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 COA E Y1798 R1841 K1844 N1845 A1846 I1871 S1872 H1873 Y32 R75 K78 N79 A80 I105 S106 H107
BS02 COA E D1772 E1817 F1820 K1821 S1827 L1828 G1829 L1834 D6 E51 F54 K55 S61 L62 G63 L68
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0008897 holo-[acyl-carrier-protein] synthase activity
Biological Process
GO:0006633 fatty acid biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:2wat, PDBe:2wat, PDBj:2wat
PDBsum2wat
PubMed19679086
UniProtP19097|FAS2_YEAST Fatty acid synthase subunit alpha (Gene Name=FAS2)

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