Structure of PDB 2w4l Chain E

Receptor sequence
>2w4lE (length=162) Species: 9606 (Homo sapiens) [Search protein sequence]
YLEWPEYFMAVAFLSAQRSKDPNSQVGACIVNSENKIVGIGYNGMPNGCS
DDVLPWRRTAENKLDTKYPYVCHAELNAIMNKNLTDVKGCSMYVALFPCN
ECAKLIIQAGIKEVIFMSDKYHDSDEATAARLLFNMAGVTFRKFIPKCSK
IVIDFDSINSRP
3D structure
PDB2w4l The Crystal Structure of Human Dcmp Deaminase
ChainE
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.4.12: dCMP deaminase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN E H84 C110 C113 H73 C99 C102
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004132 dCMP deaminase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0070694 deoxyribonucleoside 5'-monophosphate N-glycosidase activity
Biological Process
GO:0006220 pyrimidine nucleotide metabolic process
GO:0009165 nucleotide biosynthetic process
GO:0009972 cytidine deamination
GO:0043174 nucleoside salvage
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2w4l, PDBe:2w4l, PDBj:2w4l
PDBsum2w4l
PubMed
UniProtP32321|DCTD_HUMAN Deoxycytidylate deaminase (Gene Name=DCTD)

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