Structure of PDB 2q9i Chain E

Receptor sequence
>2q9iE (length=296) Species: 9606 (Homo sapiens) [Search protein sequence]
NLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKECEE
IIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFG
RKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIE
MEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGE
NRTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPN
GRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKMSMKIRPFFP
3D structure
PDB2q9i Probing the beta-chain hole of fibrinogen with synthetic peptides that differ at their amino termini
ChainE
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide E L360 E363 N364 W385 E397 R406 C407 H408 D432 M438 L197 E200 N201 W222 E234 R243 C244 H245 D269 M275
BS02 CA E D381 D383 W385 L386 D218 D220 W222 L223
BS03 CA E D261 G263 D98 G100
Gene Ontology
Molecular Function
GO:0005102 signaling receptor binding
Biological Process
GO:0007596 blood coagulation
GO:0030168 platelet activation
GO:0051258 protein polymerization
Cellular Component
GO:0005577 fibrinogen complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2q9i, PDBe:2q9i, PDBj:2q9i
PDBsum2q9i
PubMed17688324
UniProtP02675|FIBB_HUMAN Fibrinogen beta chain (Gene Name=FGB)

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