Structure of PDB 2q6w Chain E

Receptor sequence
>2q6wE (length=188) Species: 9606 (Homo sapiens) [Search protein sequence]
TRPRFLELRKSECHFFNGTERVRYLDRYFHNQEEFLRFDSDVGEYRAVTE
LGRPVAESWNSQKDLLEQKRGRVDNYCRHNYGVGESFTVQRRVHPQVTVY
PAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGD
WTFQTLVMLETVPRSGEVYTCQVEHPSVTSALTVEWRA
3D structure
PDB2q6w Crystallographic Structure of the Human Leukocyte Antigen DRA, DRB3*0101: Models of a Directional Alloimmune Response and Autoimmunity
ChainE
Resolution2.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide E R11 S13 Y26 W61 K71 R74 N77 Y78 H81 N82 V85 G86 R9 S11 Y24 W59 K69 R72 N75 Y76 H79 N80 V83 G84
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process
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Cellular Component
External links
PDB RCSB:2q6w, PDBe:2q6w, PDBj:2q6w
PDBsum2q6w
PubMed17583734
UniProtP79483|DRB3_HUMAN HLA class II histocompatibility antigen, DR beta 3 chain (Gene Name=HLA-DRB3)

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