Structure of PDB 2q5e Chain E

Receptor sequence
>2q5eE (length=179) Species: 9606 (Homo sapiens) [Search protein sequence]
CLLPEVTEEDQGRICVVIDLDETLVHSSFKPINNADFIVPIEIEGTTHQV
YVLKRPYVDEFLRRMGELFECVLFTASLAKYADPVTDLLDRCGVFRARLF
RESCVFHQGCYVKDLSRLGRDLRKTLILDNSPASYIFHPENAVPVQSWFD
DMADTELLNLIPIFEELSGAEDVYTSLGQ
3D structure
PDB2q5e Structural genomics of protein phosphatases.
ChainE
Resolution2.51 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.3.16: protein-serine/threonine phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG E D107 D109 N218 D19 D21 N130
Gene Ontology
Molecular Function
GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity
GO:0016791 phosphatase activity

View graph for
Molecular Function
External links
PDB RCSB:2q5e, PDBe:2q5e, PDBj:2q5e
PDBsum2q5e
PubMed18058037
UniProtO14595|CTDS2_HUMAN Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 (Gene Name=CTDSP2)

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