Structure of PDB 2q2q Chain E

Receptor sequence
>2q2qE (length=249) Species: 303 (Pseudomonas putida) [Search protein sequence]
TLKGKTALVTGSTSGIGLGIAQVLARAGANIVLNGFGDPAPALAEIARHG
VKAVHHPADLSDVAQIEALFALAEREFGGVDILVNNAGIQHVAPVEQFPL
ESWDKIIALNLSAVFHGTRLALPGMRARNWGRIINIASVHGLVGSTGKAA
YVAAKHGVVGLTKVVGLETATSNVTCNAICPGWVLTPLVQKQIDDRALQA
QHDLLAEKQPSLAFVTPEHLGELVLFLCSEAGSQVRGAAWNVDGGWLAQ
3D structure
PDB2q2q Cosubstrate-induced dynamics of D-3-hydroxybutyrate dehydrogenase from Pseudomonas putida.
ChainE
Resolution2.02 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) G16 S139 Y152 K156
Catalytic site (residue number reindexed from 1) G15 S138 Y151 K155
Enzyme Commision number 1.1.1.30: 3-hydroxybutyrate dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD E G12 T14 S15 G16 I17 F37 D60 L61 N87 A88 G89 L110 S139 Y152 K156 P182 W184 V185 T187 L189 V190 G11 T13 S14 G15 I16 F36 D59 L60 N86 A87 G88 L109 S138 Y151 K155 P181 W183 V184 T186 L188 V189
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003858 3-hydroxybutyrate dehydrogenase activity
GO:0016491 oxidoreductase activity

View graph for
Molecular Function
External links
PDB RCSB:2q2q, PDBe:2q2q, PDBj:2q2q
PDBsum2q2q
PubMed17958702
UniProtQ9AE70

[Back to BioLiP]