Structure of PDB 2pf4 Chain E

Receptor sequence
>2pf4E (length=163) [Search protein sequence]
MDKVLNREESLQLMDLLGLERSAWGNIPLMRKAYLKKCKEFHPDDEEKMK
KMNTLYKKMEDGVKYAHQPDFGGFWASSLNPGVDAIYCKQWPECVKKMST
NCICLLCLLRMKHENRKLYRKDPLVWVDCYCFDCFRMWFGLDLCEGTLLL
WCDIIGQTTYRDL
3D structure
PDB2pf4 Structural basis of PP2A inhibition by small t antigen.
ChainE
Resolution3.1 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN E C103 C113 C116 C94 C104 C107
BS02 ZN E H122 C138 C140 C143 H113 C129 C131 C134
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0039657 symbiont-mediated suppression of host gene expression
Cellular Component
GO:0030430 host cell cytoplasm
GO:0042025 host cell nucleus

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:2pf4, PDBe:2pf4, PDBj:2pf4
PDBsum2pf4
PubMed17608567
UniProtP03081|ST_SV40 Small t antigen

[Back to BioLiP]