Structure of PDB 2p88 Chain E

Receptor sequence

>2p88E (length=369) Species: 226900 (Bacillus cereus ATCC 14579)

MKITAIHLYAIRLPLRNPFVISYGSYSDMPSIIVKMETDEGIIGYGEGVA
DDHVTGESWESTFHTLKHTLTPALIGQNPMNIEKIHDMMDNTIYGVPTAK
AAIDIACFDIMGKKLNQPVYQLIGGRYHEEFPVTHVLSIADPENMAEEAA
SMIQKGYQSFKMKVGTNVKEDVKRIEAVRERVGNDIAIRVDVNQGWKNSA
NTLTALRSLGHLNIDWIEQPVIADDIDAMAHIRSKTDLPLMIDEGLKSSR
EMRQIIKLEAADKVNIKLMKCGGIYPAVKLAHQAEMAGIECQVGSMVESS
VASSAGFHVAFSKKIITSVELTGPLKFTKDIGNLHYDVPFIRLNEKPGLG
IEINEDTLQELTVFQDIVR

3D structure

• PDB: 2p88 Prediction and assignment of function for a divergent N-succinyl amino acid racemase.
• Chain: E
• Resolution: 2.4 Å

Enzymatic activity

• Catalytic site (original residue number in PDB): F19 A50 H53 V136 F160 K161 M162 K163 D191 N193 E218 D243 E244 G245 N265 K267 G294 S295 M296 V319 E320 L321
• Catalytic site (residue number reindexed from 1): F19 A50 H53 V136 F160 K161 M162 K163 D191 N193 E218 D243 E244 G245 N265 K267 G294 S295 M296 V319 E320 L321
• Enzyme Commision number: 5.1.1.-

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	MG	E	D191 E218 D243	D191 E218 D243

Gene Ontology

Molecular Function

• GO:0000287 magnesium ion binding
• GO:0016853 isomerase activity
• GO:0016854 racemase and epimerase activity
• GO:0016855 racemase and epimerase activity, acting on amino acids and derivatives
• GO:0036361 racemase activity, acting on amino acids and derivatives
• GO:0046872 metal ion binding

Biological Process

• GO:0006518 peptide metabolic process

External links

• PDB: RCSB:2p88, PDBe:2p88, PDBj:2p88
• PDBsum: 2p88
• PubMed: 17603539
• UniProt: Q81IL5|NSAR_BACCR N-succinyl-L-Arg/Lys racemase (Gene Name=BC_0371)