Structure of PDB 2oyh Chain E

Receptor sequence
>2oyhE (length=295) Species: 9606 (Homo sapiens) [Search protein sequence]
LRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKECEEI
IRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGR
KWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEM
EDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGEN
RTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNG
RYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKMSMKIRPFFP
3D structure
PDB2oyh Probing the gamma2 Calcium-Binding Site: Studies with gammaD298,301A Fibrinogen Reveal Changes in the gamma294-301 Loop that Alter the Integrity of the "a" Polymerization Site.
ChainE
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide E N364 M367 W385 E397 R406 C407 H408 T431 D432 M438 N200 M203 W221 E233 R242 C243 H244 T267 D268 M274
BS02 CA E D381 D383 W385 D217 D219 W221
Gene Ontology
Molecular Function
GO:0005102 signaling receptor binding
Biological Process
GO:0007596 blood coagulation
GO:0030168 platelet activation
GO:0051258 protein polymerization
Cellular Component
GO:0005577 fibrinogen complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2oyh, PDBe:2oyh, PDBj:2oyh
PDBsum2oyh
PubMed17411074
UniProtP02675|FIBB_HUMAN Fibrinogen beta chain (Gene Name=FGB)

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