Structure of PDB 2oox Chain E

Receptor sequence
>2ooxE (length=333) Species: 4896 (Schizosaccharomyces pombe) [Search protein sequence]
MDVQETQKGALKEIQAFIRSRTSYDVLPTSFRLIVFDVTLFVKTSLSLLT
LNNIVSAPLWDSEANKFAGLLTMADFVNVIKYYYQSSSFPEAIAEIDKFR
LLGLREVERKIGAIPPETIYVHPMHSLMDACLAMSKSRARRIPLIDVDGE
TGSEMIVSVLTQYRILKFISMNCKETAMLRVPLNQMTIGTWSNLATASME
TKVYDVIKMLAEKNISAVPIVNSEGTLLNVYESVDVMHLIQDGDYSNLDL
SVGEALLKRPANFDGVHTCRATDRLDGIFDAIKHSRVHRLFVVDENLKLE
GILSLADILNYIIYDKTTTPGVPEQTDNFESAV
3D structure
PDB2oox Crystal structures of the adenylate sensor from fission yeast AMP-activated protein kinase.
ChainE
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AMP E R141 T191 L195 A196 I216 S217 I303 S305 D308 R140 T190 L194 A195 I215 S216 I302 S304 D307
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016208 AMP binding
GO:0019887 protein kinase regulator activity
GO:0019901 protein kinase binding
GO:0030295 protein kinase activator activity
GO:0043531 ADP binding
Biological Process
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007165 signal transduction
GO:0010514 induction of conjugation with cellular fusion
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0031588 nucleotide-activated protein kinase complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:2oox, PDBe:2oox, PDBj:2oox
PDBsum2oox
PubMed17289942
UniProtQ10343|AAKG_SCHPO 5'-AMP-activated protein kinase subunit gamma (Gene Name=cbs2)

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