Structure of PDB 2ok7 Chain E

Receptor sequence

>2ok7E (length=254) Species: 36329 (Plasmodium falciparum 3D7) [Search protein sequence]

NFINLYTVKNPLKCKIVDKINLVRPNSPNEVYHLEINHNGLFKYLEGHTC
GIIPYYNQRCARLYSISSSNNMENLSVAIKIHKYENYGYCSGFIKNLKIN
DDIYLTGAHGYFNLPNDAIQKNTNFIFIATGTGISPYISFLKKLFAYDKN
NLYNRNSNYTGYITIYYGVYNEDSILYLNELEYFQKMYPNNINIHYVFSY
ATSFYVQDEIYKRKTEFLNLFNNYKCELYICGHKSIRYKVMDILKKKRVH
VEVY

3D structure

PDB

2ok7 Ferredoxin-NADP(+) Reductase from Plasmodium falciparum Undergoes NADP(+)-dependent Dimerization and Inactivation: Functional and Crystallographic Analysis.

Chain

Resolution

2.7 Å

3D
structure

Catalytic site residues are labeled in the structure
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Enzymatic activity

Catalytic site (original residue number in PDB)	Y103 S104 C284 E314 Y316
Catalytic site (residue number reindexed from 1)	Y64 S65 C231 E252 Y254
Enzyme Commision number	1.18.1.2: ferredoxin--NADP(+) reductase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	FAD	E	R101 L102 Y103 S104 A117 K119 H121 Y123 G136 Y137 C138 S139 T180 E314 Y316	R62 L63 Y64 S65 A78 K80 H82 Y84 G88 Y89 C90 S91 T132 E252 Y254
BS02	A2P	E	K119 T178 G179 V217 Y218 S247 Y258 Q260 H286 S288	K80 T130 G131 V169 Y170 S199 Y205 Q207 H233 S235
BS03	A2P	E	S288 Y291 K292	S235 Y238 K239

Gene Ontology

	Molecular Function
GO:0016491	oxidoreductase activity

View graph for
Molecular Function

External links

PDB	RCSB:2ok7, PDBe:2ok7, PDBj:2ok7
PDBsum	2ok7
PubMed	17258767
UniProt	C6KT68\|FENR_PLAF7 Ferredoxin--NADP reductase, apicoplast (Gene Name=FNR)

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