Structure of PDB 2o73 Chain E

Receptor sequence
>2o73E (length=164) Species: 7955 (Danio rerio) [Search protein sequence]
DINVVNALAYEDFVKLFGNVVEKCPLISAAIWSYRPFKDLADIEARISEF
IHSLPDSGKEGILRCHPDLAGRDLQSGTLTPESQEEQSQAGMTTLDSAEI
VHMYRLNSEYKERFGFPFVICARLNNKADIVRQLSERLKNRRTAELECAI
EEVKKICSLRLHSI
3D structure
PDB2o73 The structure of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase provides insights into the mechanism of uric acid degradation.
ChainE
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.1.1.97: 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 2AL E P68 L70 S84 E87 Q88 F119 V120 I121 A123 I157 P67 L69 S83 E86 Q87 F118 V119 I120 A122 I156
Gene Ontology
Molecular Function
GO:0016831 carboxy-lyase activity
GO:0051997 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase activity
Biological Process
GO:0000255 allantoin metabolic process
GO:0006144 purine nucleobase metabolic process
GO:0019628 urate catabolic process
Cellular Component
GO:0005777 peroxisome

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External links
PDB RCSB:2o73, PDBe:2o73, PDBj:2o73
PDBsum2o73
PubMed17428786
UniProtA1L259|URAD_DANRE 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase (Gene Name=urad)

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