Structure of PDB 2nxx Chain E

Receptor sequence
>2nxxE (length=234) Species: 7070 (Tribolium castaneum) [Search protein sequence]
ISPEQEELIHRLVYFQNEYEHPSEEDVKRIINDGEDQCDVRFRHITEITI
LTVQLIVEFAKRLPGFDKLLREDQIALLKACSSEVMMFRMARRYDVQTDS
ILFVNNQPYSRDSYNLAGMGETIEDLLHFCRTMYSMRVDNAEYALLTAIV
IFSERPALIEGWKVEKIQEIYLEALRAYVDNRRKPKPGTIFAKLLSVLTE
LRTLGNQNSEMCFSLKLKNKKLPPFLAEIWDVDL
3D structure
PDB2nxx Structural and functional characterization of a novel type of ligand-independent RXR-USP receptor.
ChainE
Resolution2.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 P1A E E330 H331 P332 I361 T362 T365 R402 M403 R406 I414 F416 V417 Y427 E20 H21 P22 I48 T49 T52 R89 M90 R93 I101 F103 V104 Y114
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
GO:0035100 ecdysone binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0035076 ecdysone receptor signaling pathway
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2nxx, PDBe:2nxx, PDBj:2nxx
PDBsum2nxx
PubMed17673910
UniProtA1JUG3

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